Malakhova Maya Vladimirovna

Malakhova Maya Vladimirovna
Malakhova Maya Vladimirovna

Contacts:
Phone (work): (499)-246-45-70
E-mail: maja_m@mail.ru
Mobile phone: +7 9167262064
Skype: malahova88

Personal data
PhD (biological science) member of the staff laboratory of Microbial Molecular Genetics since 2004 year (the date of its foundation). Graduated on biochemistry from 2-nd Moscow ordena Lenina medical institute after the name of N.I. Pirigov. In the year 1997 .graduated as a post doc in Research Institute of Physico-chemical Меdicine. Defended PhD theses on: “The influence of oxidated derivatives of beta carotene on the metabolism of cholsterin in the cultured human cells”
Scientific interests
Molecular genetics of M.tuberculosis и N.gonorrhoeae
The study of molecular genetic mechanisms of antibiotic resistance formation in N.gonorrhoeae.
Molecular methods of identification and typing of viruses and pathogenic bacteria.
Basic achievements
Development of detection systems for genetic determinants of drug resistance in N.gonorrhoeae basing on mini sequencing technology and MALDI-ToF mass spectrometry.
Development of system for HB virus genotyping.
M.tuberculosis full genome sequencing.
Revealing of molecular mechanism of spectinomycin-resistance in N.gonorrhoeae.
Main publications

  • Malakhova MV, Orlova VF, Karpov VA, Govorun VM, Khalilov EM. beta-Carotene oxidation products effect cholesterol biosynthesis and growth of human epidermoid carcinoma cultured cells. Biull Eksp Biol Med. 1998 Sep;126(9):321-4. Russian.
  • Il'ina EN, Malakhova MV, Vereshchagin VA, Govorun VM, Sergienko VI, Zubkov MM, Vasil'ev MM, Kubanova AA. Molecular typing of N. gonorrhoeae strains prevalent in the Russian Federation. Bull Exp Biol Med. 2003 Aug;136(2):179-82.
  • Malakhova MV, Vereshchagin VA, Il'ina EN, Govorun VM, Zubkov MM, Priputnevich TV, Kisina VI, Kubanova AA. Analysis of genetic markers of N. gonorrhoeae resistance to beta-lactam antibiotics. Bull Exp Biol Med. 2006 May;141(5):610-5.
  • Borovskaya AD, Malakhova MV, Vereshchagin VA, Il'ina EN, Govorun VM, Priputnevich TV, Al-Hafagi N, Kubanova AA. Analysis of the contribution of molecular mechanisms into formation of gonoccocal resistance to tetracycline. Bull Exp Biol Med. 2007 Sep;144(3):432-
  • Malakhova MV, Vereshchagin VA, Il'ina EN, Govorun VM, Filimonova OIu, Grudinina SA, Sidorenko SV. MALDI-ToF mass-spectrometry in analysis of genetically determined resistance of Streptococcus pneumoniae to fluoroquinolones. Antibiot Khimioter. 2007;52(1-2):10-7. Russian.
  • Malakhova MV, Ilina EN, Govorun VM, Shutko SA, Dudina KR, Znoyko OO, Klimova EA, Iushchuk ND. Hepatitis B virus genetic typing using mass-spectrometry. Bull Exp Biol Med. 2009 Feb;147(2):220-5.
  • Zubritskiĭ AV, Il'ina EN, Strel'chenko SA, Malakhova MV, Lenev SV, Skliarov OD, Panin AN, Govorun VM. Investigation of molecular mechanisms of aminoglycoside resistance in Salmonella. Antibiot Khimioter. 2011;56(9-10):7-12. Russian.
  • Ilina E.N., Borovskaya A.D., Malakhova M.V., Vereshchagin V.A., Kubanova A.A., Kruglov A.N., Svistunova T.S., Gazarian A.O., Maier T., Kostrzewa M., Govorun V.M. Direct bacterial profiling by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry for identification of pathogenic Neisseria. // J Mol Diagn. – 2009. – V. 11 – No 1. – P. 75 - 86.
  • The only mutation in ribosomal protein S5 confers the resistance of Neisseria gonorrhoeae to spectinomycin. Elena N. Ilina, Maya V. Malakhova, Nina Yu. Oparina, Alexandra D. Borovskaya, Vadim M. Govorun. 18 th International Pathogenic Neisseria Conference (IPNC). 09-14 September. 2012. Würzburg. Germany